GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| THCA | trans | rs41266839 | 1 | rs13195401 | chr6:26463574 | RNF5P1 | chr8:38457695-38458775:- | 0.74 | 6.45 | 2.75E-10 | Schizophrenia |
| THCA | trans | rs41266839 | 1 | rs13195401 | chr6:26463574 | ZFP57 | chr6:29640171-29648887:- | 0.84 | 7.79 | 4.28E-14 | Schizophrenia |
| THCA | trans | rs41266839 | 1 | rs13195401 | chr6:26463574 | ZNF389 | chr6:28129551-28137375:+ | -0.64 | -6.25 | 8.95E-10 | Schizophrenia |
| THCA | trans | rs41266839 | 1 | rs13195402 | chr6:26463575 | RNF5P1 | chr8:38457695-38458775:- | 0.74 | 6.45 | 2.75E-10 | Schizophrenia |
| THCA | trans | rs41266839 | 1 | rs13195402 | chr6:26463575 | ZFP57 | chr6:29640171-29648887:- | 0.84 | 7.79 | 4.28E-14 | Schizophrenia |
| THCA | trans | rs41266839 | 1 | rs13195402 | chr6:26463575 | ZNF389 | chr6:28129551-28137375:+ | -0.64 | -6.25 | 8.95E-10 | Schizophrenia |
| THCA | trans | rs853679 | 1 | rs13200462 | chr6:28218199 | BTN3A2 | chr6:26365398-26378546:+ | -0.54 | -10.42 | 4.69E-23 | Depression |
| THCA | trans | rs1056667 | 1 | rs1321479 | chr6:26501897 | ZNF322B | chr9:99957633-99961910:- | -0.53 | -9.99 | 1.77E-21 | Educational attainment |
| THCA | trans | rs1056667 | 1 | rs1321480 | chr6:26532742 | ZNF322B | chr9:99957633-99961910:- | 0.54 | 10.29 | 1.46E-22 | Educational attainment |
| THCA | trans | rs1056667 | 1 | rs1321481 | chr6:26538210 | ZNF322B | chr9:99957633-99961910:- | 0.54 | 10.32 | 1.12E-22 | Educational attainment |
| THCA | trans | rs41266839 | 1 | rs13220495 | chr6:26441640 | RNF5P1 | chr8:38457695-38458775:- | 0.75 | 6.37 | 4.35E-10 | Schizophrenia |
| THCA | trans | rs41266839 | 1 | rs13220495 | chr6:26441640 | ZFP57 | chr6:29640171-29648887:- | 0.83 | 7.49 | 3.39E-13 | Schizophrenia |
| THCA | trans | rs995030 | 1 | rs1355062 | chr12:88906789 | ATP6V1B1 | chr2:71162998-71192560:+ | -0.41 | -5.94 | 5.43E-9 | Testicular germ cell tumor |
| THCA | trans | rs853679 | 1 | rs1419183 | chr6:28242794 | BTN3A2 | chr6:26365398-26378546:+ | -0.5 | -9.8 | 9.06E-21 | Depression |
| THCA | trans | rs965513 | 1 | rs1443438 | chr9:100550028 | BMPR1A | chr10:88516396-88684944:+ | -0.24 | -6.19 | 1.26E-9 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |